Drew Brees was nearly flawless. As usual, the Oakland Raiders were miserable on the road.

Brees completed 22-of-25 passes for 281 yards and a career-high five touchdowns as the San Diego Chargers demolished Oakland, 42-14, handing the Raiders their 13th consecutive road loss.

Brees set a personal-best and team-best in completion percentage at 88 percent and became the first Chargers quarterback to throw for five scores in a game since Dan Fouts in 1982. Fouts had six TD passes in a 1981 game at Oakland.

"I was having fun," Brees said. "Obviously, this was a huge game and we were absolutely ready to play. I think it showed. Everything was just kind of rolling. It was one of those days."

"(Brees) was outstanding," Chargers coach Marty Schottenheimer said. "He made all of the right throws and that contributed to what we were able to do on offense as a whole."

San Diego (5-3), which scored on six of its first seven possessions, has averaged 30 points in winning four of its last five games and leads the league with 219 points. During this run, Brees has thrown for 1,121 yards and 11 TDs.

"As an offense, we're really starting to see how good we can be and it's exciting," Brees said.

"I think, right now, that we have as good an understanding of what it is we're trying to do as we've had since I've been here," Schottenheimer said.

Oakland (2-6) gave up 30 points for the fifth consecutive game - all losses - for the first time in franchise history and gained only 22 yards against the league's second-best rushing defense.

"We are just not a good team," Raiders cornerback Charles Woodson said. "No point in pointing any blame. It's real simple. We're not buying into the system we are running and it is just not happening for us."

Brees got things going early by hitting tight end Justin Peelle for a 17-yard score on San Diego's first scoring drive. It was Peelle's second TD and fourth catch of the season.

LaDainian Tomlinson , who missed some practice time this week with a strained groin, broke Chuck Muncie's franchise record for rushing touchdowns when he reached the end zone for the 44th time, scoring in the first quarter to give the Chargers a 14-0 lead.

Tomlinson gained 71 yards on 19 carries before sitting out most of the second half. He came into the game with 589 yards in three previous games against the Raiders, including a career-high 243 last December.

"I've had a good career so far," Tomlinson said. "Hopefully, I can continue to build on this tradition."

Keenan McCardell , playing his second game with San Diego since his trade from the Tampa Bay Buccaneers , grabbed his first touchdown when he hauled in a 13-yard pass to cap a nine-play, 80-yard drive in the second quarter, making the score 21-7.

Moments before the half, Tim Dwight got into the act when he caught a 23-yard touchdown that gave San Diego a 28-7 advantage. Brees was 14-of-16 for 189 yards at halftime, while the Chargers defense held the Raiders to just seven rushing yards.

Tight end Antonio Gates began the game as the league's third-leading receiver and caught a pair of scoring passes in the third quarter, including a 4th-and-goal reception that put the Chargers up 42-7. Gates caught five passes for 63 yards.

The frustration reached the boiling point for the Raiders after the sixth San Diego touchdown when defensive tackle Warren Sapp came off the field screaming at coach Norv Turner, who simply nodded and turned away.

"I don't think we take anything away from this game that is positive," Turner said. "It's obvious that we're not capable of putting a drive together, putting a defensive stand together. They played a lot faster than us. They made a lot more plays than us."

Oakland's Kerry Collins was 24-of-39 for 263 yards and a touchdown with two interceptions for the Raiders, who have the second-longest current road losing streak, behind the Arizona Cardinals (17).

"Every time you lose, it is everybody's fault," Collins said. "It's both sides of the ball. It's not this guy or that guy. We have to be better offensively. I know that. I understand that. It's up to us whether we want to do it or not."

The victory, the most lopsided of the series since 1961, allowed San Diego to surpass its win total from last year and gave Schottenheimer a 22-7 career record against Oakland.